Inactivation of Autophagy Leads to Changes in Sebaceous Gland Morphology and Function

July 2018 in “ Experimental dermatology ”

Heidemarie Rossiter, Gerald Stübiger, Marion Gröger, Ulrich König, Флориан Грубер, Supawadee Sukseree, Veronika Mlitz, Maria Buchberger, Olga Oskolkova, Valery N. Bochkov, Leopold Eckhart, Erwin Tschachler

autophagy sebaceous gland Atg7 gene keratinocytes sebocyte proliferation lipid sebum free fatty acids cholesterol fatty acid methyl esters lipid homeostasis skin oil glands skin cells fatty acids skin oil lipid balance

Studysummary This study found that autophagy plays a role in sebaceous gland function and sebum composition control in mice lacking the Atg7 gene in keratinocytes.

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research Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis

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research Abnormal Differentiation of Epidermis in Transgenic Mice Constitutively Expressing Cyclooxygenase-2 in Skin

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