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    Glossary FOXA1

    gene encoding a transcription factor influencing hair follicle development

    FOXA1, or Forkhead Box A1, is a gene that encodes a transcription factor involved in regulating the expression of other genes. It plays a crucial role in the development and function of various tissues, including the liver, lungs, and prostate. In the context of hair biology, FOXA1 can influence hair follicle development and cycling, and its dysregulation may be implicated in conditions like alopecia.

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    1. Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies Scientific Reports · 2025 · 1 citations
    2. Gene expression of FOXA1 and CCL2 in different phenotypes of infertile women with polycystic ovarian syndrome Egyptian Journal of Basic and Applied Sciences · 2025
    3. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Science · 2016 · 142 citations
    4. Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis Genes & development · 2010 · 95 citations
    5. FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma Journal of Investigative Dermatology · 2004 · 92 citations
    6. FOXO1, TGF-β Regulation and Wound Healing International Journal of Molecular Sciences · 2014 · 87 citations
    7. FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program Frontiers in Immunology · 2013 · 69 citations
    8. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    9. Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation Developmental Biology · 2008 · 67 citations
    10. Evidence That the Satin Hair Mutant Gene Foxq1 Is among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 during Hair Follicle Differentiation 2006 · 65 citations
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