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GlossaryFOXA3

gene encoding a protein that regulates hair follicle development

FOXA3 is a gene that encodes a transcription factor, which is a protein that helps turn specific genes on or off by binding to nearby DNA. In the context of hair biology, FOXA3 has been implicated in the regulation of hair follicle development and cycling, potentially influencing conditions like alopecia.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice

research Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice

556 citations , September 2008 in “Genes & Development”

Wnt signaling is vital for cell growth, development, and cancer research.

research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma

55 citations , March 2015 in “Carcinogenesis”

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

research Small Molecules and Small Molecule Drugs in Regenerative Medicine

51 citations , November 2013 in “Drug Discovery Today”

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

research The Pharmacology of Regenerative Medicine

47 citations , July 2013 in “Pharmacological Reviews”

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

research Fibroblasts: Origins, Definitions, and Functions in Health and Disease

488 citations , July 2021 in “Cell”

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

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