Oxidative Stress and Alopecia Areata

June 2023 in “ Frontiers in medicine ”

Yongkui Ma, Zhan Sun, Yumei Li, Huji Xu

alopecia areata autoimmune disease hair loss immune privilege collapse genetic factors oxidative stress antioxidants hair follicle-immune privilege AA OS

TLDR Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

The review discusses Alopecia areata (AA), an autoimmune disease causing hair loss, and its unclear pathogenesis, which is thought to involve immune privilege collapse, genetic factors, allergies, microbiota, and psychological stress. The focus of the review is on oxidative stress (OS), an imbalance between oxidation and antioxidant systems, and its association with AA. It suggests that oxidative stress may trigger the collapse of hair follicle-immune privilege and could be linked to the development of AA. The review also proposes that antioxidants might serve as a potential supplementary therapy for AA in the future.

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Research cited in this study

18 / 18 results

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