Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata

    December 2018 in “ Skin pharmacology and physiology
    Nazli Dizen-Namdar, Fatma Emel Koçak, Mehtap Kıdır, Gülben Sarıcı, Hasan Tak, İrfan Altuntaş
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    Studysummary This study found that in people with alopecia areata, oxidative stress indicators were higher and specific enzyme activities were lower compared to healthy controls, suggesting oxidative stress's significant role in disease pathogenesis.
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    The study evaluated serum paraoxonase, arylesterase, prolidase activities, and oxidative stress in patients with alopecia areata. The researchers aimed to understand the biochemical changes associated with this condition. The findings indicated that patients with alopecia areata had altered enzyme activities and increased oxidative stress compared to healthy controls. These results suggested that oxidative stress and enzyme activity changes might play a role in the pathogenesis of alopecia areata.
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