Antioxidants and Lipid Peroxidation Status in the Blood of Patients with Alopecia
January 2000
in “
Cell biochemistry and function
”
New to Vitamin E? There is a guide in the encyclopedia. Read the guide → Studysummary This study observed that patients with alopecia had increased lipid peroxidation and decreased antioxidants, including lower beta-carotene, GSH levels, and GSH-Px activity, compared to healthy controls.
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The study aimed to assess the levels of antioxidants and lipid peroxidation in the blood of 37 patients with alopecia compared to 34 healthy controls. It found that patients with alopecia had significantly lower levels of beta-carotene, reduced glutathione (GSH), and glutathione peroxidase (GSH-Px) activity, while thiobarbituric-acid reactive substances (TBARS) levels were significantly higher, indicating increased lipid peroxidation. However, vitamin E levels did not differ significantly between the two groups. These findings suggested a potential role of increased lipid peroxidation and decreased antioxidants in alopecia.
