16 citations
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December 2018 in “Skin pharmacology and physiology” This study found that in people with alopecia areata, oxidative stress indicators were higher and specific enzyme activities were lower compared to healthy controls, suggesting oxidative stress's significant role in disease pathogenesis.
June 2025 in “Turkish Journal of Dermatology” This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.
October 2023 in “Benha Journal of Applied Sciences” This study found that male patients with androgenetic alopecia had lower serum levels of the antioxidant enzyme paraoxonase 1 compared to healthy controls.
July 2022 in “International Journal of Contemporary Medicine” This study found that patients with alopecia areata have significantly lower serum PON1 levels compared to controls, indicating a potential link between oxidative stress and the pathogenesis of the disease.
April 2017 in “Journal of Investigative Dermatology” This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.