Evaluation of Paraoxonase 1 Serum Level in Male Androgenetic Alopecia Patients

    October 2023 in “ Benha Journal of Applied Sciences
    Shimaa Desokey, Khaled Mohey El-Din Monib, Mohamed Saber Hussein, Asmaa Mohamed
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    TLDR Men with male pattern baldness have lower levels of the antioxidant PON1.
    The research paper "Evaluation of Paraoxonase 1 Serum Level in Male Androgenetic Alopecia Patients" is a case-control study involving 60 male patients with androgenetic alopecia (AGA) and 20 healthy volunteers. The study aimed to measure the serum levels of Paraoxonase 1 (PON1), an antioxidant that prevents the oxidation of low-density lipoprotein (LDL), in AGA patients and compare it with healthy controls. The results showed that the serum PON1 and HDL levels were significantly lower in AGA patients than in the controls. The study concluded that the lower level of PON1 observed in AGA patients might be due to increased oxidative stress.
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