Lab Quality Management and Methodology

The document detailed research findings that established connections between androgenetic alopecia (AGA) and various health conditions such as metabolic syndrome (MetS), obstructive sleep apnea (OSA), and diabetes mellitus (DM). A study involving 75 male AGA patients found a 38.5% prevalence of MetS, indicating the need for MetS screening in young Indian males with AGA. The presence of the T allele in the OLR1: IVS4-73 C>T SNP was significantly associated with an increased risk of MetS. High insulin levels were observed in 40 MetS patients regardless of OSA, and an inverse relationship between testosterone levels and metabolic parameters was noted in 50 male MetS patients. High-sensitivity C-reactive protein (hs-CRP) levels, which were elevated in a sample of 100 MetS patients, were suggested as a potential tool for assessing MetS risk. Leptin levels were found to be higher in 40 MetS patients and were influenced by the presence of OSA. Furthermore, a study of 60 diabetic patients showed that higher D-dimer levels were associated with a longer duration of DM and the presence of coronary artery disease (CAD), proposing D-dimer as a marker for CAD risk in DM patients.