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GlossaryLeptin

hormone from fat cells that signals to reduce appetite

Leptin is a hormone produced by fat cells that helps regulate body weight by signaling the brain to reduce appetite and increase energy expenditure. It plays a crucial role in maintaining energy balance and is involved in various physiological processes, including metabolism and immune function.

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research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ

218 citations , October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

research Low Leptin Level in an Obese Hyperandrogenic Woman – Potential Marker for Androgen-Secreting Tumor

4 citations , January 2007 in “Gynecological endocrinology”

Low leptin levels in obese women with high testosterone may indicate a tumor that secretes male hormones.

research The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia

February 2023 in “Clinical, Cosmetic and Investigational Dermatology”

Higher leptin and lower vitamin D levels may contribute to male pattern baldness.

research The Effect of Sleep Extension on Metabolic and Androgen Parameters of Healthy Women with Habitual Short Sleep Duration: Pilot Study

December 2023 in “Palestinian medical and pharmaceutical journal/Palestinian medical & pharmaceutical journal”

Increasing sleep by 41 minutes daily for a month showed no significant changes in metabolism or hormone levels in healthy women.

research The Effects of High-Intensity Interval Training on Vaspin, Adiponectin, and Leptin Levels in Women with Polycystic Ovary Syndrome

21 citations , September 2019 in “Archives of Physiology and Biochemistry”

High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.

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community Korean 2021 study shows efficacy of sulforaphane.

in Treatment 48 upvotes 4 years ago

Sulforaphane shows potential for hair regrowth, with users reporting reduced shedding and regrowth. Some users combine it with Minoxidil and finasteride for better results.

community PSA: Don't buy cheap toppik off ebay

9 upvotes 8 years ago

Cheap Toppik from eBay is likely fake and doesn't stick well to hair. Buy from official website for better quality.

community Listening to you guys and letting it grow. Little over 2 years progress.

in Progress Pictures 83 upvotes 1 year ago

A 42-year-old uses dutasteride, topical minoxidil, microneedling, and dermastamping for hair regrowth, reporting no side effects and noticeable progress over two years. The user takes 0.5mg of dutasteride and varies microneedling frequency, seeing early signs of new growth.

community Guys. Your hairloss and your mental health issues connected to your hairloss are two separate issues that require two separate treatments

in Chat 356 upvotes 3 years ago

Hair loss and the importance of not letting it affect one's self-worth. The conversation includes advice on treatments such as taking medication, like Minoxidil and Finasteride, and other methods to manage hairloss, such as buzzing your head or seeking professional help.

community 5 months on min+fin and letting my hair grow

in Progress Pictures 258 upvotes 1 month ago

The user shared progress pictures after 5 months of using topical minoxidil (1ml per day) and oral finasteride (1mg per day) for hair growth, with no side effects reported. The user also mentioned having a hair transplant in December and uses pH-neutral baby shampoo.

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