Alopecia and the Metabolic Syndrome

    September 2017 in “ Clinics in Dermatology
    Cheryl Jia Ling Lie, Choon Fong Liew, Hazel H Oon
    Image of study
    TLDR Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
    The document from 2018 examines the link between androgenetic alopecia (AGA) and metabolic syndrome (MetS), showing a significant association, especially in men. AGA, a common hair loss form, involves androgens like dihydrotestosterone (DHT) causing follicular miniaturization. MetS comprises conditions that raise the risk of cardiovascular disease, stroke, and diabetes. Studies reviewed suggest a strong connection between AGA and MetS, as well as AGA and MetS components such as dyslipidemia, hypertension, and coronary artery disease. The document also explores AGA's relationship with other metabolic conditions like PCOS and Cushing's syndrome, advocating for MetS screening in AGA patients. It mentions a case-control study with 80 Thai men and a larger study with 7126 patients but calls for more research, particularly on women. Additionally, the document discusses the role of nutrient deficiencies in hair loss and the unclear effects of supplementation, the commonality of hair loss after bariatric surgery, and the limited evidence linking lifestyle factors to AGA. It also differentiates alopecia areata (AA) as autoimmune and not strongly linked to MetS. The conclusion suggests that AGA patients could be screened for MetS to prevent cardiovascular issues, but more studies are needed to establish definitive guidelines.
    Discuss this study in the Community →

    Research cited in this study

    41 / 41 results

    Related Community Posts Join

    6 / 1000+ results
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  865 upvotes 5 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 6 months ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community Do we have to be junkies? That's funny

      in Research/Science  12 upvotes 9 months ago
      The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

      community Update on my progress after 10,5 months

      in Progress Pictures  150 upvotes 2 months ago
      The user has been using a combination of oral finasteride, oral dutasteride, topical and oral minoxidil, microneedling, and keto shampoo for hair loss, experiencing significant shedding recently. Suggestions include simplifying the regimen by dropping finasteride and topical minoxidil, and possibly adding RU58841, while others advise maintaining the current approach for consistent results.

    Similar Research

    5 / 1000+ results