Association Between Alopecia Areata, Psoriasis Vulgaris, Thyroid Disease, And Metabolic Syndrome

    December 2013 in “ Journal of Investigative Dermatology Symposium Proceedings ”
    Rim Ishak, Melissa Piliang
    TLDR Autoimmune and metabolic issues are linked, and treating one may worsen another.
    The document discussed two young women with severe psoriasis, androgen excess, metabolic syndrome, thyroiditis, and alopecia areata (AA), who both progressed to treatment-resistant alopecia universalis. It highlighted the complex interplay between autoimmune disorders and metabolic syndrome, emphasizing the need for comprehensive laboratory assessments in AA patients. The study noted that while psoriasis and psoriatic arthritis are linked to higher risks of other autoimmune disorders, the association with metabolic syndrome in AA had not been previously reported. The findings suggested that successful psoriasis treatment might exacerbate AA, and dermatologists should screen for autoimmune and metabolic abnormalities in these patients. Further research was recommended to explore the link between AA and cardiovascular/metabolic diseases.
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