Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-Control Study on 100 Patients in a Tertiary Care Hospital in South India

January 2018 in “ Indian Journal of Endocrinology and Metabolism ”

K C Dharam Kumar, Yadalla Hari Kishan Kumar, Vivekananda Neladimmanahally

androgenetic alopecia metabolic syndrome AGA MetS male pattern baldness

Studysummary This study found that patients with androgenetic alopecia had a higher prevalence of metabolic syndrome compared to healthy controls.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study investigated the association between androgenetic alopecia (AGA) and metabolic syndrome (MetS) in 100 patients with AGA and 100 controls at a tertiary care hospital in South India. It found a significantly higher prevalence of MetS in AGA cases (53%) compared to controls (17%) and a positive correlation between the severity of AGA and MetS prevalence. The study concluded that AGA is significantly associated with MetS, suggesting that early screening for MetS in AGA patients could help prevent future complications through early lifestyle modifications.

View this study on journals.lww.com →

Discuss this study in the Community →

Research cited in this study

15 / 15 results

research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

24 citations , January 2015 in “International Journal of Trichology”

This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

34 citations , January 2014 in “Indian Dermatology Online Journal”

This study supports evaluating metabolic syndrome and insulin resistance in young males with advanced androgenic alopecia to potentially reduce future cardiovascular and type 2 diabetes risks.

research Association of Premature Androgenetic Alopecia and Metabolic Syndrome in a Young Indian Population

16 citations , January 2014 in “International Journal of Trichology”

This study found that male Indian patients under 30 with early androgenetic alopecia were more likely to have metabolic syndrome compared to age-matched controls.

research Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease

49 citations , May 2013 in “JAMA Dermatology”

This study found that moderate to severe androgenetic alopecia is an independent predictor of increased mortality risk from diabetes mellitus and heart disease in both sexes.

research Gender-Specific Association of Androgenetic Alopecia with Metabolic Syndrome in a Middle-Aged Korean Population

37 citations , April 2012 in “British Journal of Dermatology”

This study found that among middle-aged Korean women, those with metabolic syndrome had a higher risk of androgenetic alopecia, while no significant association was observed in men.

research The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia

42 citations , January 2011 in “European Journal of Dermatology”

In this study, higher scores of HOMA-IR and FIRI suggested that male patients with early-onset androgenetic alopecia may have insulin resistance, although no significant differences in metabolic syndrome were found compared to controls.

research The Association of Insulin Resistance and Metabolic Syndrome in Early Androgenetic Alopecia

18 citations , December 2010 in “PubMed”

This study found that early androgenic alopecia patients showed increased prevalence of insulin resistance and metabolic syndrome, suggesting they should be monitored for coronary artery disease over the long term.

research Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study

110 citations , July 2010 in “Journal of The American Academy of Dermatology”

Hair loss linked to higher heart disease risk in both men and women.

research Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects

41 citations , January 2009 in “International Journal of Trichology”

This study found that 58% of men aged 30-50 had androgenic alopecia, with disease severity increasing with age and many being candidates for medical treatment or hair transplantation.

research Evaluation of Lipid Levels in Androgenetic Alopecia Compared with Control Group

27 citations , March 2008 in “Journal of The European Academy of Dermatology and Venereology”

Men with a certain type of hair loss (AGA) have higher bad cholesterol and lower good cholesterol levels, making them more likely to get heart disease.

research Association of Androgenetic Alopecia and Hypertension

34 citations , August 2007 in “PubMed”

This study found a strong association between androgenetic alopecia and hypertension in Caucasian men, independent of age.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations , September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness

54 citations , May 1998 in “Urology”

This study demonstrates that patients with benign prostatic hyperplasia have a higher severity and frequency of male pattern baldness compared to a control group.

research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp

227 citations , January 1998 in “Journal of Endocrinology”

This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations , September 1977 in “British Journal of Dermatology”

This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.