Metabolic Syndrome in Androgenetic Alopecia Patients: Is Serum Regulated on Activation, Normal T-Cell Expressed and Secreted the Missing Link?

October 2020 in “ Journal of Cosmetic Dermatology ”

Amany Ibrahim Mustafa, Walid A Abdel Halim, Fawzy Eman, Doaa M. Elhabak

androgenetic alopecia metabolic syndrome serum RANTES biomarker AGA

TLDR Possible link between hair loss and metabolic syndrome, with RANTES as a potential clue.

The study suggests a potential link between androgenetic alopecia and metabolic syndrome, with higher levels of serum RANTES found in AGA patients with metabolic syndrome. RANTES may be the missing link between the two conditions. The study involved 80 participants with AGA and proposes that RANTES may be a valuable biomarker for identifying metabolic syndrome in individuals with androgenetic alopecia. However, more research is needed to confirm this connection.

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Research cited in this study

11 / 11 results

research Androgenetic Alopecia: A Review

153 citations, March 2017 in “Endocrine”

Male pattern baldness involves genetics, hormones, and needs better treatments.

research Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis

48 citations, October 2014 in “International Journal of Cardiology”

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

34 citations, July 2014 in “Indian Dermatology Online Journal”

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

research Sex Hormone–Binding Globulin and Risk of Hyperglycemia in Patients With Androgenetic Alopecia

36 citations, July 2011 in “Journal of The American Academy of Dermatology”

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

research Androgenetic Alopecia and Insulin Resistance: Are They Truly Associated?

35 citations, April 2011 in “International Journal of Dermatology”

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

research Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey

69 citations, April 2010 in “British Journal of Dermatology”

Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.

research Hypertension and Aldosterone Levels in Women with Early-Onset Androgenetic Alopecia

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Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

research Androgenic Alopecia and Insulin Resistance: Are They Really Related?

28 citations, March 2009 in “Clinical and Experimental Dermatology”

There is no significant link between male pattern baldness and insulin resistance.

research Established Risk Factors for Coronary Heart Disease Are Unrelated to Androgen-Induced Baldness in Female-to-Male Transsexuals

57 citations, January 2004 in “Journal of Endocrinology”

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations, September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations, September 1977 in “British Journal of Dermatology”

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

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