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Glossary Low-Density Lipoprotein

transports cholesterol to tissues, potentially causing artery blockages

Low-Density Lipoprotein (LDL), often referred to as "bad cholesterol," is a type of lipoprotein responsible for transporting cholesterol from the liver to various tissues throughout the body. High levels of LDL can lead to the buildup of cholesterol in the arteries, increasing the risk of cardiovascular diseases such as heart attacks and strokes.

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Research

5 / 1000+ results

research Low sex hormone-binding globulin is associated with low high-density lipoprotein cholesterol and metabolic syndrome in women with PCOS

71 citations , June 2006 in “Human Reproduction”

This study found that in young Taiwanese women with PCOS, low sex hormone-binding globulin levels were associated with low HDL cholesterol levels, independent of insulin resistance and obesity.

research Mendelian randomization analysis of the causal relationship between low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and androgenic alopecia

January 2026 in “Medicine”

This study found that elevated LDL-C levels increased the risk of developing androgenic alopecia, whereas HDL-C levels showed no significant effect.

research Both low circulating insulin-like growth factor-1 and high-density lipoprotein cholesterol are associated with hair loss in middle-aged women

6 citations , March 2016 in “British Journal of Dermatology”

This study reports that low levels of HDL cholesterol and IGF-1 were associated with a higher risk of hair loss in middle-aged women, but causal relationships remain uncertain.

research Low level of high-density lipoprotein cholesterol is solely associated with greater severity of male androgenetic alopecia: A cross-sectional study of Thai population

May 2015 in “Journal of The American Academy of Dermatology”

research Der Effekt von oxidiertem Low Density Lipoprotein im Vergleich zu Zytokin-induzierter Inflammation auf die Differenzierungseigenschaften von humanen gingivalen mesenchymalen Stammzellen

January 2025 in “Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)”

In this study, human gingival mesenchymal stem cells responded differently to inflammation mediated by oxidized low-density lipoprotein (oxLDL) compared to cytokines; oxLDL significantly reduced cell proliferation but had less negative impact on differentiation characteristics.

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Community Join

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community Finasteride - 5 years and my expierience

128 upvotes 3 weeks ago

A 26-year-old shared their 5-year experience using finasteride and minoxidil for hair loss, noting initial improvements but later experiencing reduced libido and erection quality, leading them to switch from oral to topical finasteride. They advise starting with a low-dose topical solution and emphasize making informed decisions, acknowledging that while finasteride is effective, it can have side effects.

community Dutasteride and elevated (LDL) cholesterol

1 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Dutasteride is way more effective than Finasteride (Study)

in Research/Science 184 upvotes 1 year ago

Dutasteride is more effective than Finasteride for hair loss, with similar safety profiles. Individual responses vary, and factors like Minoxidil use and age differences may influence results.

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Learn

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learn Platelet-Rich Plasma

Is Platelet-Rich Plasma more effective when combined with topical treatments or supplements? Small, mostly high-risk-of-bias trials suggest adding PRP to minoxidil may improve hair density; the evidence is low to very low certainty, and no trial has tested PRP with supplements.

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Experts

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Clinics

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