Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management

August 2021 in “ Clinical Reviews in Allergy & Immunology ”

Cheng Zhou, Xiangqian Li, Chen Wang, Jianzhong Zhang

alopecia areata JAK inhibitors adalimumab etanercept secukinumab platelet-rich plasma apremilast IL-2 therapy PRP interleukin-2

TLDR JAK inhibitors show promise for treating alopecia areata, but more research is needed.

The document provided an update on alopecia areata, focusing on its causes, diagnosis, and treatment options. JAK inhibitors were highlighted as a promising treatment, with studies suggesting their effectiveness. Biologics like adalimumab, etanercept, and secukinumab showed mixed results, with some studies indicating limited efficacy. Platelet-rich plasma (PRP) therapy demonstrated potential benefits for hair regrowth. The document also discussed the use of apremilast, which had varying success rates, and the potential of low-dose IL-2 therapy to modulate immune responses. Overall, it emphasized the complexity of treating alopecia areata and the need for further research to develop more effective therapies.

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