Benefit of Different Concentrations of Intralesional Triamcinolone Acetonide in Alopecia Areata: An Intrasubject Pilot Study

In this pilot study involving 4 patients with untreated patchy alopecia areata, intralesional injections of 2.5 mg/mL triamcinolone acetonide were found to be as effective as 5 or 10 mg/mL concentrations in promoting hair growth and increasing hair density and caliber, with fewer side effects such as skin atrophy. The study suggested that using the lowest effective concentration (2.5 mg/mL) minimizes local side effects and allows for a greater volume of injection, which could be beneficial for treating more extensive scalp alopecia areata. Further research with a larger sample size was recommended to validate these findings.