Alopecia Areata After Dupilumab for Atopic Dermatitis

January 2018 in “ JAAD case reports ”

Krystal Mitchell, J. Levitt

alopecia areata dupilumab atopic dermatitis biologic therapy AA AD

TLDR Dupilumab for eczema may cause hair loss.

Dupilumab, a biologic therapy approved for atopic dermatitis (AD), was generally considered safe based on over 1,000 adult patient exposures, with conjunctivitis being the most notable side effect. However, a case was reported where a patient developed alopecia areata (AA) within 5 weeks of starting dupilumab treatment for AD, highlighting a potential adverse effect not previously emphasized.

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Research cited in this study

1 / 1 results

research The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm

77 citations , June 2017 in “Advances in Therapy”

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

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The conversation is about someone who has been taking finasteride for hair loss without success, considering switching to dutasteride or giving up treatment. Suggestions include trying dutasteride, microneedling, infrared therapy, multivitamins, and high-concentration topical solutions combining finasteride and dutasteride.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

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Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

community I 24F have gone from a full head of hair to ~30% of hair in 2 weeks

in Female 49 upvotes 3 years ago

A 24 year old female experiencing rapid, unexplained hair loss over the course of two weeks and looking for advice. Treatments suggested include Rogaine, finasteride, minoxidil, RU58841, and seeing a dermatologist.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 4 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.

in Treatment 5 years ago

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

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research Cytokine-Targeting Biologic Therapies for Alopecia Areata: A Comprehensive Review of Mechanism of Action, Clinical Efficacy, and Adverse Events

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Dupilumab and ustekinumab are promising treatments for alopecia areata, showing significant hair regrowth.

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