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    A Hair-Raising History of Alopecia Areata

    January 2020 in “ Experimental Dermatology ”
    David Broadley, Kevin J. McElwee
    Studysummary This review outlines the historical and ongoing evolution in understanding and treating alopecia areata, highlighting current research frontiers in genetics, immune mechanisms, and potential new treatments, but reports no new results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 29

    1. Cyclosporine for Moderate-to-Severe Alopecia Areata: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Efficacy and Safety Journal of the American Academy of Dermatology · 2019
    2. JAK Inhibitors and Alopecia Areata Lancet · 2019
    3. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    4. JAK Inhibitors for Treatment of Alopecia Areata ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2018
    5. Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata Journal of Investigative Dermatology · 2015
    6. Hair Growth: Focus on Herbal Therapeutic Agents Current Drug Discovery Technologies · 2015
    7. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
    8. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    9. The Role of Hair Follicle Immune Privilege Collapse in Alopecia Areata: Status and Perspectives Journal of Investigative Dermatology Symposium Proceedings · 2013
    10. The Effect of Oral Cyclosporine in the Treatment of Severe Alopecia Areata Cutaneous and ocular toxicology · 2013
    11. Blocking Potassium Channels (Kv1.3): A New Treatment Option for Alopecia Areata? Journal of Investigative Dermatology · 2013
    12. Alopecia Areata as a Model for T Cell-Dependent Autoimmune Diseases Experimental Dermatology · 2012
    13. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    14. Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model Veterinary Dermatology · 2009
    15. The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results Experimental dermatology · 2008
    16. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    17. Alefacept for Alopecia Areata Archives of dermatology · 2005
    18. Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-Mediated Root Sheath Disruption in Advance of Overt Hair Loss Veterinary pathology · 2003
    19. Dietary Soy Oil Content and Soy-Derived Phytoestrogen Genistein Increase Resistance to Alopecia Areata Onset in C3H/HeJ Mice Experimental Dermatology · 2003
    20. Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata Experimental dermatology · 2001
    21. Third International Research Workshop on Alopecia Areata Journal of Investigative Dermatology · 1999
    22. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    23. Autoantibodies to Hair Follicles in C3H/HeJ Mice With Alopecia Areata-Like Hair Loss Journal of Investigative Dermatology · 1997
    24. The Etiology and Pathogenesis of Alopecia Areata Journal of Dermatological Science · 1994
    25. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994
    26. Failure of Passive Transfer of Serum From Patients With Alopecia Areata and Alopecia Universalis to Inhibit Hair Growth in Transplants of Human Scalp Skin Grafted Onto Nude Mice British Journal of Dermatology · 1992
    27. Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 1984
    28. Topical Minoxidil in Alopecia Areata Journal of The American Academy of Dermatology · 1981
    29. Treatment of Alopecia Areata With Steroid Solution Archives of dermatology · 1972

    Related research 8

    1. Time to Loss of Response for Dupilumab in Ophiasis-Pattern Alopecia Areata JAAD case reports · 2021
    2. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    3. A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0–18 Years) in Kota Region, South-East Rajasthan Indian Journal of Dermatology · 2019
    4. Topical and Intralesional Therapies for Alopecia Areata Dermatologic therapy · 2011
    5. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    6. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    7. Diagnosis of Hair Loss: Clinical Features of Common Causes PubMed · 1992
    8. Diagnosis and Management of the Hair Loss Patient PubMed · 1987