Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model

    January 2009 in “ Veterinary Dermatology ”
    John P. Sundberg, Kathleen A. Silva, Weidong Zhang … Steven Black
    Studysummary This study found that recombinant hepatitis B vaccine may increase the risk of alopecia areata onset in older predisposed mice but larger trials suggest this effect might lie within normal variation.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on europepmc.org →
    Discuss this study in the Community →

    Research cited in this study 13

    1. The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results Experimental dermatology · 2008
    2. Alopecia Areata in a Rhesus Monkey (Macaca Mulatta) Journal of Medical Primatology · 2007
    3. Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata The American Journal of Human Genetics · 2007
    4. Failure to Induce Alopecia Areata in C3H/HeJ Mice with Exogenous Interferon Gamma Journal of experimental animal science · 2006
    5. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005
    6. The Pathogenesis of Alopecia Areata in Rodent Models Journal of Investigative Dermatology Symposium Proceedings · 2003
    7. The Histopathology of Alopecia Areata in Vertical and Horizontal Sections Dermatologic Therapy · 2001
    8. Murine Cytomegalovirus Is Not Associated With Alopecia Areata in C3H/HeJ Mice Journal of Investigative Dermatology · 1998
    9. Comparison of Alopecia Areata in Human and Nonhuman Mammalian Species Pathobiology · 1998
    10. Hair Loss After Routine Immunizations JAMA · 1997
    11. Alopecia Areata in Korea (1982–1994) The Journal of Dermatology · 1995
    12. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994
    13. Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 1984