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    Glossary MicroRNAs

    MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in regulating gene expression by binding to messenger RNAs (mRNAs) and inhibiting their translation or promoting their degradation. In the context of hair loss and hair biology, miRNAs are involved in various processes such as hair follicle development, cycling, and the response to stressors that can lead to conditions like androgenetic alopecia. Key distinguishing characteristics of miRNAs include their ability to modulate multiple target genes simultaneously, which can influence cellular pathways related to hair growth and loss. Understanding the role of miRNAs in hair biology may offer insights into potential therapeutic targets for hair loss treatments.

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    1. MicroRNA control of signal transduction Nature Reviews Molecular Cell Biology · 2010 · 1066 citations
    2. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    3. MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2 Stem cells · 2012 · 123 citations
    4. MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway Journal of Cell Biology · 2014 · 103 citations
    5. Importance of microRNAs in skin morphogenesis and diseases. PubMed · 2008 · 70 citations
    6. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration Cell Cycle · 2012 · 56 citations
    7. MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes The Journal of Clinical Endocrinology and Metabolism · 2016 · 50 citations
    8. Control by a hair’s breadth: the role of microRNAs in the skin Cellular and Molecular Life Sciences · 2012 · 41 citations
    9. MicroRNAs in skin tissue engineering Advanced drug delivery reviews · 2015 · 39 citations
    10. Identification of microRNAs in Wool Follicles during Anagen, Catagen, and Telogen Phases in Tibetan Sheep PLoS ONE · 2013 · 37 citations
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    Community 4

    1. Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles Reddit · 12 Jun 2023
    2. MicroRNA science breakthrough? Softening stem cells Reddit · 5 Jun 2023
    3. Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser Reddit · 4 Mar 2024
    4. Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases Reddit · 21 Apr 2024

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