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GlossaryDifferentially Expressed miRNAs

small RNA molecules with varying expression levels in different conditions

Differentially Expressed miRNAs (microRNAs) are small RNA molecules that show different levels of expression in different conditions, such as between healthy and diseased tissues. These variations can help identify specific biological processes or pathways that are altered in conditions like alopecia, providing insights into potential targets for treatment or diagnosis.

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research Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.

research Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways

14 citations, March 2017 in “Genes and immunity”

Certain microRNAs may help treat alopecia areata by targeting immune pathways.

research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Roles of miRNAs in Sheep Hair Follicle Development

5 citations, October 2022 in “BMC genomics”

Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.

research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development

July 2022 in “Research Square (Research Square)”

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

research Discovery and Functional Analysis of Secondary Hair Follicle miRNAs During Annual Cashmere Growth

3 citations, January 2023 in “International journal of molecular sciences”

Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 120 upvotes 7 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 3 months ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 6 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 487 upvotes 4 weeks ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

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