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GlossaryDifferential Stripping

technique selectively removes specific layers for detailed analysis

Differential Stripping is a technique used in the study of hair and skin to selectively remove specific layers or components. This method allows researchers to analyze the structure and composition of different layers, such as the cuticle, cortex, and medulla in hair, or the epidermis and dermis in skin, to better understand their individual properties and functions.

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research Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal

34 citations, July 2010 in “Expert Opinion on Drug Delivery”

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles

162 citations, August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

research Follicular Transport Route: Research Progress and Future Perspectives

211 citations, February 2009 in “European journal of pharmaceutics and biopharmaceutics”

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

research Targeting to the Hair Follicles: Current Status and Potential

142 citations, January 2010 in “Journal of dermatological science”

Hair follicles are promising targets for delivering drugs effectively.

research Hair Follicles, Their Disorders, and Their Opportunities

48 citations, May 2008 in “Drug Discovery Today: Disease Mechanisms”

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

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community Research Backed Dutasteride Simulator (Serum/Scalp DHT included for all doses)

in Finasteride/Dutasteride 100 upvotes 3 months ago

A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 4 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 103 upvotes 6 months ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 9 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

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