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Glossary Differentially Expressed Proteins

proteins with varying expression levels between different biological conditions

Differentially Expressed Proteins (DEPs) are proteins that show significant differences in their levels of expression between two or more biological conditions, such as healthy versus diseased tissue. Identifying DEPs can help researchers understand the molecular mechanisms underlying various conditions, including alopecia, by highlighting which proteins are upregulated or downregulated in response to specific factors.

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research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations , April 2023 in “Animals”

This study utilized EDAR gene-targeted cashmere goats to identify 732 differentially expressed genes and 140 proteins associated with abnormal hair growth, providing insights into the regulatory mechanisms of cashmere follicle development.

research [Proteomics-based screening of differentially expressed proteins in skin of Chinese merino fine sheep (JunKen type) of different gender].

1 citations , October 2022 in “PubMed”

This study identified 674 differentially expressed proteins in the skin tissues of male and female Chinese merino sheep, suggesting gender-specific molecular mechanisms that may affect wool traits.

research Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

8 citations , January 2015 in “Genetics and molecular research”

This study identified four proteins that differ between Type III and non-Type III hair in Yangtze River Delta white goats, contributing to understanding the development of high-quality brush hair.

research Discovery of differentially expressed genes in cashmere goat (Capra hircus) hair follicles by RNA sequencing

5 citations , January 2016 in “Genetics and Molecular Research”

This study identified 617 differentially expressed genes in cashmere goat hair follicles, which are involved in key biological processes and provide insights into hair follicle development.

research Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

61 citations , April 2013 in “PloS one”

This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

121 upvotes 2 years ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

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