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    Glossary Differentially Methylated Regions

    areas of DNA with varying methylation patterns between samples

    Differentially Methylated Regions (DMRs) are specific areas of DNA where the pattern of methylation—a chemical modification that can regulate gene expression—differs between two or more samples, such as between healthy and diseased tissues. These regions are important in studying conditions like alopecia, as changes in methylation can influence the activity of genes involved in hair growth and loss.

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    1. Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats Frontiers in Genetics · 2020 · 39 citations
    2. Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling BMC genomics · 2018 · 28 citations
    3. Analysis of Genome DNA Methylation at Inherited Coat Color Dilutions of Rex Rabbits Frontiers in genetics · 2021 · 7 citations
    4. Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells Frontiers in Immunology · 2022 · 1 citations
    5. Analysis of genome DNA methylation at inherited coat-color dilutions of Rex Rabbits Research Square (Research Square) · 2020 · 1 citations
    6. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    7. Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies International journal of molecular sciences · 2023
    8. 1340 Basal keratinocytes exhibit age-related epigenetic and transcriptomic alterations resulting in an altered metabolic profile Journal of Investigative Dermatology · 2023
    9. Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome Frontiers in Cell and Developmental Biology · 2021 · 9 citations
    10. Dynamic changes of genomic methylation profiles at different growth stages in Chinese Tan sheep 2021 · 35 citations
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