Hair Follicles, Their Disorders, and Their Opportunities

    May 2008 in “ Drug Discovery Today: Disease Mechanisms ”
    Alexa Patzelt, Fanny Knorr, Ulrike Blume‐Peytavi … Jürgen Lademann
    Studysummary This review discusses recent advancements in understanding hair follicles, their disorders, and potential therapeutic opportunities, but it reports no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 33

    1. Sexual Hormones in Human Skin Hormone and metabolic research · 2007
    2. Alopecia Areata: Overview and Treatment Options International Journal of Dermatology · 2007
    3. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007
    4. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    5. Diagnosis of Hyperandrogenism: Biochemical Criteria Best Practice & Research Clinical Endocrinology & Metabolism · 2006
    6. Investigation of Differences in Follicular Penetration of Particle- and Nonparticle-Containing Emulsions by Laser Scanning Microscopy Laser Physics · 2006
    7. Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles Journal of Investigative Dermatology · 2006
    8. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    9. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    10. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    11. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    12. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    13. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    14. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    15. Bacterial Diseases of the Skin Journal of Long-Term Effects of Medical Implants · 2005
    16. Time and Depth Resolved Visualization of the Diffusion of a Lipophilic Dye into the Hair Follicle of Fresh Unfixed Human Scalp Skin Journal of Controlled Release · 2004
    17. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    18. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    19. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004
    20. Gene Delivery to the Hair Follicle Journal of Investigative Dermatology Symposium Proceedings · 2003
    21. Follicular Liposomal Delivery Systems Journal of liposome research · 2002
    22. Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro Journal of drug targeting · 2002
    23. Hair and Systemic Disease Dermatologic Clinics · 2001
    24. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    25. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    26. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    27. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    28. Immunopathology of the Human Hair Follicle Dermatologic Clinics · 1999
    29. Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne Journal of Cutaneous Medicine and Surgery · 1998
    30. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    31. Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes Journal of Pharmaceutical Sciences · 1997
    32. Vitiligo Seminars in Cutaneous Medicine and Surgery · 1997
    33. A Study of Etretinate-Induced Alopecia British Journal of Dermatology · 1990

    Related research 3

    1. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
    2. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    3. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001