research Hair follicles, their disorders and their opportunities
This review discusses recent advancements in understanding hair follicles, their disorders, and potential therapeutic opportunities, but it reports no new clinical findings.
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5 / 1000+ results research A9. Excess hair: physical and pharmacological treatments
This article reviews the effectiveness of laser technology and Eflornithine cream as modern methods for reducing unwanted hair growth and reports no new clinical results.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.
research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators and Myostatin Inhibitors
This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.
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5 / 201 resultscommunity Could a reversed SARM designed for the scalp serve as a replacement for oral Dut and Fin?
The conversation discusses the potential of developing a selective oral SARM to target androgen activity in the scalp and skin, as an alternative to oral Dutasteride and Finasteride, which have systemic side effects. It also mentions Clascoterone and RU58841 as topical treatments for hair loss.
community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?
The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.
community Creatine in People Who Take DHT
Finasteride users have mixed experiences with creatine; some experience increased hair loss, while others do not. Finasteride's DHT-blocking effects might counteract any DHT increase from creatine, but individual responses vary.
community The Real Cause Of Androgenetic Alopecia
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
community Does RU58841 potentially cause cancer?
RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.
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2 / 801 resultslearn Bicalutamide
a nonsteroidal anti-androgen, most commonly used orally for women
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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