Disorders of Hair Growth and the Pilosebaceous Unit: Facts and Controversies

    October 2013 in “ Clinics in Dermatology
    Márcia Ramos‐e‐Silva, Rodrigo Pirmez
    Image of study
    TLDR Experts don't fully agree on how to diagnose certain hair growth disorders and more research is needed to understand them better.
    The document from 2013 reviews the controversies surrounding hair growth disorders, specifically alopecia areata incognita (AAI), pseudopelade of Brocq (PPB), and the link between psoriasis and alopecia. It notes the lack of consensus on diagnostic criteria for AAI and PPB, as well as the unclear epidemiology of PPB. The document also discusses psoriatic alopecia, which can manifest in various patterns and may not be directly caused by psoriasis, although hair loss can occur in psoriatic lesions, often with regrowth after treatment. Additionally, it mentions a study by Doyle et al. that found anti-TNF-α agents, used for treating chronic inflammatory diseases, can induce psoriatic lesions and alopecia, suggesting this should be considered a separate diagnostic entity. The study observed psoriasiform and alopecia areata-like changes in scalp biopsies, with features that distinguish it from primary psoriatic alopecia. The document emphasizes the need for further research to better understand these disorders and improve diagnostic criteria.
    Discuss this study in the Community →

    Research cited in this study

    17 / 17 results

    Related Community Posts Join

    6 / 1000+ results

      community 22F. Should I even bother getting a biopsy? Is there any point?

       8 upvotes 8 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  933 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 1 year ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

      in Chat  15 upvotes 7 months ago
      A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.

    Similar Research

    5 / 1000+ results