Acute Diffuse and Total Alopecia of the Female Scalp Associated with Borrelia Infection

    Ekta K Bhardwaj, Ralph M. Trüeb
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    TLDR A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.
    In 2015, a case was reported where a woman experienced acute diffuse and total alopecia, which is a form of hair loss recognized as a variant of alopecia areata (AA), in association with a Borrelia infection (acrodermatitis chronica atrophicans). Alopecia areata is considered an autoimmune disease targeting hair follicles, and infections have been previously reported to potentially trigger this condition. Conversely, alopecia could also serve as an indicator for undiagnosed infections. The patient's treatment with intravenous ceftriaxone successfully resolved the Borrelia infection, and the use of topical clobetasol foam led to the complete regrowth of her hair.
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