Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study

    September 2019 in “ Dermatology practical & conceptual ”
    Aurora Alessandrini, Michela Starace, Francesca Bruni, Nicolò Brandi, Carlotta Baraldi, Cosimo Misciali, Pier ­Alessandro Fanti, Bianca Maria Piraccini
    Image of study
    TLDR The study concluded that AAI and DAA are forms of the same disease, with different symptoms in men and women, and that corticosteroid treatment is effective.
    The 5-year study conducted from 2012 to 2017 examined Alopecia Areata Incognita (AAI) and Diffuse Alopecia Areata (DAA), involving 107 AAI patients and 25 DAA patients. The research found that AAI and DAA are different presentations of the same disease, with AAI more common in women and DAA more common in men. Trichoscopy was crucial for diagnosis, with yellow dots and short vellus hairs being common findings. Histopathology showed peribulbar lymphocytic infiltrate in both conditions, with DAA showing more severe inflammatory damage. The most effective treatment was intralesional corticosteroids, with 70% of cases responding well. After 8 months of therapy, 52.4% of AAI patients and 60% of DAA patients were in remission.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 1000+ results

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 2 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

      in Chat  15 upvotes 8 months ago
      A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       7 upvotes 8 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  936 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

      community Is there any chance of improvement?

      in Minoxidil  7 upvotes 2 years ago
      A 19-year-old experiencing severe hair loss since 16 is using a treatment regimen of 5% minoxidil, 0.1% finasteride topical solution, 3% procapil hair serum, and 0.5 mg dutasteride daily. They are concerned about the effectiveness and potential shedding phase, with advice suggesting noticeable changes in 6 to 8 months.

    Related Research

    6 / 6 results