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    GlossaryVellus Hairs

    fine, short, lightly pigmented hairs covering most of the body

    Vellus hairs, often referred to as "peach fuzz," are fine, short, and lightly pigmented hairs that cover most of the human body. Unlike terminal hairs, which are thicker and darker, vellus hairs play a role in thermoregulation and are typically less noticeable. They can be found in areas such as the face, arms, and back, and are more prominent in children and women.

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Are These Long vellus Hair an Indikator for regrowth?

      in Is this regrowth?  1 upvotes 1 year ago
      A user, 35M, has been using oral finasteride for 5 years and 5% minoxidil for 3 years, which stopped hair loss but didn't promote regrowth. After starting RU58841 5 months ago, they noticed long, translucent hairs and are asking if these hairs will darken and how to encourage this.

      community 3-month update on the microneedling-only project

      in Microneedling  86 upvotes 3 years ago
      A 3-month update on a microneedling-only project to treat hair loss, which has not had significant results in terms of thicker hair but may have seen some acceleration in hair growth and an increase in vellus hairs. The user plans to continue the journey for 6 months before making any changes, such as adding minoxidil or finasteride.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  173 upvotes 1 week ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  210 upvotes 3 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.