Bimatoprost Versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study

    January 2015 in “ Dermatology ”
    Hesham Zaher, Heba I. Gawdat, Rehab A. Hegazy, Marwa A. Hassan
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    TLDR Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.
    In a pilot study involving 30 adult patients with patchy scalp alopecia areata (AA), bimatoprost 0.03% solution demonstrated a significantly higher mean hair regrowth rate (48.95%) compared to mometasone furoate 0.1% cream (22.4%), as well as a quicker initial response time (1.48 weeks vs. 3.57 weeks). Bimatoprost-treated patches also had a lower incidence of resistance (16.7% vs. 43.3%) and relapse (4% vs. 11.8%) than corticosteroid-treated patches, with no side effects reported, while corticosteroid-treated patches had side effects in 58.8% of cases. The study suggests that bimatoprost is a safe and more effective alternative to corticosteroids for the treatment of scalp AA, although it is more expensive. Further large-scale studies are recommended to confirm these findings.
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