Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata

    March 2009 in “ Journal of The American Academy of Dermatology ”
    Ingrid Roseborough, Hester H. Lee, Jennifer Chwalek, Robert L. Stamper, Vera H. Price
    From the encyclopedia
    Latanoprost →

    glaucoma medication with hair follicle stimulant effects

    Bimatoprost →

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    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

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    Studysummary This study found that latanoprost and bimatoprost, when applied cutaneously to the eyelids, did not induce appreciable eyelash regrowth in patients with alopecia areata over 16 weeks. Our plain-language summary of this paper — not a Tressless recommendation.
    In 2009, a 16-week, randomized, controlled study was conducted to evaluate the efficacy of topical latanoprost and bimatoprost ophthalmic solutions in promoting eyelash growth in patients with alopecia areata (AA). The study involved 11 adult patients with AA who had experienced more than 50% bilateral eyelash loss for 6 months or longer. The patients were randomized to receive either latanoprost or bimatoprost, which they applied directly to the affected upper and lower eyelid margins of one eye only, once daily. The untreated contralateral eye served as the control. The results showed that no appreciable eyelash regrowth was noted on clinical assessment of eyelid margins or on review of digital photographs. The study concluded that topical latanoprost and bimatoprost ophthalmic solutions were not effective in promoting eyelash growth in patients with AA.
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