TLDR 5 mg/mL of triamcinolone acetonide is most effective for hair regrowth with fewer side effects.
This systematic review and meta-analysis evaluated the efficacy and tolerability of different concentrations of intralesional triamcinolone acetonide for treating focal alopecia areata. Seven studies with 543 participants were included. Hair regrowth rates were 62.3% for concentrations less than 5 mg/mL, 80.9% for 5 mg/mL, and 76.4% for 10 mg/mL. Skin atrophy occurred in 3.33% of subjects treated with 5 mg/mL and 20% with 10 mg/mL. The analysis suggested that 5 mg/mL offered the best risk-benefit ratio, but further randomized studies were recommended to determine the lowest effective concentration.
128 citations,
February 2016 in “British Journal of Dermatology” Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
391 citations,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
36 citations,
January 2010 in “International Journal of Trichology” Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations,
November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
110 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
