Alopecia Areata: Review and Update

February 2005 in “ Anais Brasileiros de Dermatologia ”

Evandro A. Rivitti

The review article analyzed the clinical, histopathological, etiopathogenic aspects, and current therapies for alopecia areata as of 2005. It emphasized the classification of alopecia areata as an autoimmune disease with a genetic basis and discussed potential pathophysiological mechanisms. The article also reviewed contemporary treatments, particularly for severe forms of the disease, focusing on topical immunomodulatory therapies using squaric acid dibutylester and diphenylcyclopropenone, along with their possible mechanisms of action.

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research Alopecia Areata Update

391 citations , January 2010 in “Journal of The American Academy of Dermatology”

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

research Treatment of Alopecia Areata with Topical Corticosteroid: Double-Blind Randomized Prospective Study in Children

6 citations , February 2003 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Topical corticosteroid was not more effective than placebo for children's alopecia areata, and atopy did not change treatment results.

research Sulfasalazine for Alopecia Areata

62 citations , April 2002 in “Journal of the American Academy of Dermatology”

Sulfasalazine may help regrow hair in severe alopecia areata cases.

research Alopecia Areata: Diagnosis and Management

48 citations , May 1999 in “International Journal of Dermatology”

Alopecia areata is an unpredictable autoimmune hair loss condition, treated based on severity, with half of patients regrowing hair within a year without treatment.

research Treatment of Widespread Alopecia Areata in Young Patients with Monthly Oral Corticosteroid Pulse

48 citations , July 1998 in “Pediatric Dermatology”

Monthly oral corticosteroid pulses effectively treat widespread alopecia areata in young patients.

research Hair Regrowth

118 citations , April 1998 in “Dermatologic Clinics”

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

research Treatment of Alopecia Areata

48 citations , October 1996 in “Dermatologic clinics”

Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.

research Cytokines and Growth Factors Influence Hair Growth In Vitro: Possible Implications for the Pathogenesis and Treatment of Alopecia Areata

91 citations , March 1996 in “Archives of Dermatological Research”

Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.

research Alopecia Areata in a Patient with Candidiasis-Endocrinopathy Syndrome: Unsuccessful Treatment Trial with Diphenylcyclopropenone

16 citations , January 1995 in “Dermatology”

The treatment for alopecia areata with diphenylcyclopropenone was unsuccessful.

research Alopecia Areata in Aging C3H/HeJ Mice

178 citations , June 1994 in “Journal of Investigative Dermatology”

Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.

Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation

research Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation

41 citations , November 1993 in “Journal of The American Academy of Dermatology”

DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.

Alopecia Areata: A Review of Treatments and Their Efficacy

research The Treatment of Alopecia Areata

21 citations , September 1987 in “PubMed”

Corticosteroid injections are the most effective treatment for alopecia areata.

research Double-Blind, Placebo-Controlled Evaluation of Topical Minoxidil in Extensive Alopecia Areata

104 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.

research Topical Photochemotherapy for Alopecia Areata

63 citations , April 1985 in “Journal of the American Academy of Dermatology”

Topical PUVA can cause temporary hair regrowth in some alopecia areata patients but doesn't change the long-term outcome.

research Alopecia Totalis: Significant Hair Regrowth with Fluocinolone Acetonide Cream

22 citations , March 1963 in “Archives of dermatology”

A woman regrew her hair significantly using a corticosteroid cream with a plastic cover.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.