Alopecia Totalis: Significant Hair Regrowth with Fluocinolone Acetonide Cream

    March 1963 in “ Archives of dermatology
    KENNETH A. GILL
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    Studysummary This case report describes hair regrowth in a patient with alopecia totalis using fluocinolone acetonide cream applied under thin plastic films.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 34-year-old woman with alopecia totalis of 5 years duration experienced significant hair regrowth after being treated with 0.025% fluocinolone acetonide cream under an occlusive plastic dressing. The treatment involved applying the cream and covering it with a plastic film for 48 hours every 72 hours. After 3.5 months, her hair grew to 3 cm, and by September 1962, it reached 5 cm with normal texture and color. The patient showed no systemic side effects, and the treatment's success suggests that the corticosteroid acts locally, possibly facilitated by the occlusive dressing.
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