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research 080 Mouse models of alopecia areata: C3H/HeJ mice versus the humanized AA mouse model

April 2019 in “Journal of Investigative Dermatology”

This paper discusses two preclinical models for studying alopecia areata and finds that testing new therapeutic agents should involve both the C3H/HeJ mouse model and the humanized mouse model for comprehensive insights.

research Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata

12 citations , March 2016 in “BBA clinical”

This study found that intracellular Toll-like receptors were significantly up-regulated in peripheral blood mononuclear cells of alopecia areata patients, suggesting a potential role in inflammatory signaling and pathogenesis.

Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy

research Impaired responses of peripheral blood mononuclear cells to T-cell stimulants in alopecia areata patients with a poor response to topical immunotherapy

4 citations , July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

This study found that alopecia areata patients who responded poorly to topical immunotherapy had impaired peripheral blood mononuclear cell responses to T-cell stimulants.

Effect of Diode Pumping Solid State Laser with Wavelength 589 nm on Gene Expression of Interleukin-2 and Interferon-Gamma in Human T-Lymphocytes

research Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-gamma Lowercase in human T-lymphocytes

September 2024 in “Journal of the Pakistan Medical Association”

In this experimental study, laser irradiation significantly altered the gene expression of cytokines in cultured human T-cell lymphocytes, suggesting that such laser light may photobiomodulate cytokine production in vitro.

Possible Immunomodulating Effect of Retinol on Cytokine Secretion in Patients with Recurrent Furunculosis

research Possible Immunomodulating Effect of Retinol on Cytokines Secretion in Patients with Recurrent Furunculosis

4 citations , July 2017 in “Archivum Immunologiae et Therapiae Experimentalis”

This study observed that patients with recurrent furunculosis had different cytokine profiles compared to healthy subjects and that retinol stimulation altered cytokine secretion in both groups.

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community 4 months!! We making progress!!

506 upvotes 1 year ago

A user shared their successful hair regrowth journey using 0.5 mg Dutasteride, 2.5 mg oral Minoxidil, and Biotin gummies, after switching from Finasteride due to insomnia. They highlighted the importance of brushing the scalp for blood flow and reported significant progress in four months without side effects.

community Nice product I discovered, thought I would share.

in Treatment 456 upvotes 1 year ago

A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

community Old study where balding man in his 70s burned his scalp and regrew all his hair

177 upvotes 5 months ago

The conversation discusses unconventional methods for hair regrowth, including scalp trauma like burning or microneedling, and compares them to treatments like Minoxidil and Finasteride. It highlights skepticism about these methods and the body's unpredictable healing responses.

community Dutasteride actually has different half lives depending on dose

in Research/Science 37 upvotes 1 year ago

Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Hair Transplant

How is the cost of a hair transplant calculated? The cost of a hair transplant is primarily based on the number of grafts needed.
Can a hair transplant be done without shaving? Yes, hair transplants can be done without shaving, but eligibility varies.
Is a hair transplant permanent? Transplanted hair is generally permanent but requires ongoing care to maintain results.

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.
How long does a scalp micropigmentation session take? Each scalp micropigmentation session typically takes 2 to 4 hours.

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Hair Loss Specialist
Will Quaye
Crawley, England, United Kingdom

Will Quaye