Effect of Cellular Blood Components on Chemotherapy-Induced Alopecia

September 2019 in “ The journal of investigative dermatology/Journal of investigative dermatology ”

Christina Stamatiou, Assuan Lens, Carmen Perez, Sylvia Daunert, Joaquín J. Jiménez

chemotherapy-induced alopecia Mononuclear Cells Platelet Rich Plasma Ara-C cyclophosphamide etoposide IL-1 alopecia CIA MC PRP CTX VP-16

TLDR Mononuclear cells may protect against certain chemotherapy-induced hair loss.

The study investigated the protective effects of Mononuclear Cells (MC) and Platelet Rich Plasma (PRP) on chemotherapy-induced alopecia (CIA) using a young rat model. Three chemotherapeutic agents were tested: Ara-C, cyclophosphamide (CTX), and etoposide (VP-16). The control group received PBS, while other groups received PRP or MC. All groups developed complete body alopecia. MC provided excellent protection against CIA induced by Ara-C, likely due to IL-1 release, but offered no protection against CTX or VP-16. PRP did not protect against any chemotherapeutic agents. The study concluded that specific blood cells, particularly MC, may offer protection from CIA depending on the chemotherapy used.

View this study on jidonline.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 30 results

community 6 week update fellas, 5mg oral minoxidil. Pics are 2nd June – 10th July

in Progress Pictures 2 years ago

, you can find it online with a script This user was discussing their progress with hair loss treatments including 5mg oral Minoxidil and combining 3mg oral Minoxidil with MTF HRT. They also discussed side effects of increased body hair in other parts of the body.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community It works. About a 1 year transformation.

in Progress Pictures 613 upvotes 1 year ago

A user's experience with hair loss treatments, specifically Minoxidil and finasteride, which they have used without side effects for a year. Other users shared their experiences and advice about potential side effects and supplements to help.

community Don't postpone treatments now with the allure and promise of future treatments.

in Treatment 89 upvotes 4 years ago

The conversation advises against waiting for future hair loss treatments and suggests using proven treatments like Finasteride and Minoxidil. Some users regret not starting treatment earlier, while others discuss the effectiveness and safety of current treatments and the potential of microneedling.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community ~3 years on fin and alpecin shampoo

in Progress Pictures 289 upvotes 7 months ago

The user has been using finasteride and Alpecin shampoo for about three years, reporting thicker hair but an unchanged hairline. They are happy with their hair progress, noting the most improvement in the past five months, and mention a slight decrease in libido.

Related Research

2 / 2 results

research Platelet-Rich Plasma Effect on Androgenetic Alopecia and Female Pattern Hair Loss

1 citations, December 2019 in “Journal of skin and stem cell”

PRP shows promise for short-term hair growth, especially in young men.

research Olanzapine Induced Hair Loss: A Case Report

9 citations, October 2012 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology”

Stopping the drug olanzapine can reverse hair loss caused by it.