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GlossaryEtoposide

chemotherapy drug that inhibits DNA replication in cancer cells

Etoposide, also known as VP-16, is a chemotherapy drug used to treat various types of cancer, including lung cancer, testicular cancer, and certain types of lymphomas. It works by inhibiting the enzyme topoisomerase II, which is essential for DNA replication and cell division, thereby preventing cancer cells from multiplying.

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VP-16-213 (Etoposide): The Mandrake Root from Issyk-Kul

research VP-16-213 (Etoposide): The Mandrake Root from Issyk-Kul

79 citations , January 1982 in “The American Journal of Medicine”

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

research A Soy-Derived Immunostimulating Peptide Inhibits Etoposide-Induced Alopecia in Neonatal Rats

17 citations , March 2004 in “Journal of Investigative Dermatology”

Soymetide-4 from soy can prevent hair loss caused by a cancer drug in rats.

research FPRL1 Receptor Agonist Peptides Prevent Etoposide-Induced Alopecia in Neonatal Rats

8 citations , June 2004 in “Journal of Investigative Dermatology”

Certain peptides can prevent hair loss in young rats caused by a cancer drug.

Lysocellin, a Metabolite of the Novel Drug Alopestatin, Induces G1 Arrest and Prevents Cytotoxicity Induced by Etoposide

research Lysocellin, a Metabolite of the Novel Drug Alopestatin, Induces G1 Arrest and Prevents Cytotoxicity Induced by Etoposide

1 citations , April 2006 in “International Journal of Oncology”

Lysocellin helps stop cell damage from etoposide and may prevent hair loss.

research Etoposide Sensitizes CT26 Colorectal Adenocarcinoma to Radiation Therapy in BALB/c Mice

January 2005 in “世界胃肠病学杂志：英文版（电子版）”

Etoposide makes radiation therapy more effective against tumors without major side effects.

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