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    Glossary Cyclophosphamide

    chemotherapy drug that interferes with DNA replication in cells

    Cyclophosphamide, also known as Cytoxan, is a chemotherapy drug used to treat various types of cancer and certain autoimmune diseases. It works by interfering with the DNA replication process in rapidly dividing cells, which helps to slow or stop the growth of cancer cells. However, it can also affect healthy cells, leading to side effects such as hair loss (alopecia) and increased risk of infections.

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    Research 10 of 938

    1. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005 · 106 citations
    2. Sequential Therapy for Diffuse Proliferative and Membranous Lupus Nephritis: Cyclophosphamide and Prednisolone Followed by Azathioprine and Prednisolone 1995 · 80 citations
    3. Cyclophosphamide and rituximab in frequently relapsing/steroid-dependent nephrotic syndrome Pediatric Nephrology · 2015 · 39 citations
    4. Cyclophosphamide: As bad as its reputation? Long-term single centre experience of cyclophosphamide side effects in the treatment of systemic autoimmune diseases Schweizerische medizinische Wochenschrift · 2014 · 39 citations
    5. Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone. PubMed · 1994 · 36 citations
    6. Acute and Long-term Toxicity of Cyclophosphamide 2007 · 30 citations
    7. Treatment with ImuVert/JV-Acetylcysteine Protects Rats from Cyclophosphamide/ Cytarabine-Induced Alopecia Cancer investigation · 1992 · 26 citations
    8. Topical application of cyclosporin A induces rapid-remodeling of damaged anagen hair follicles produced in cyclophosphamide administered mice Journal of Dermatological Science · 2001 · 24 citations
    9. Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse (DCP) Therapy The Journal of Dermatology · 2003 · 20 citations
    10. Preventive effects of cedrol against alopecia in cyclophosphamide-treated mice Environmental Toxicology and Pharmacology · 2016 · 14 citations
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