TLDR Alopecia areata is an autoimmune disease that targets hair follicles.
Alopecia areata, an inflammatory disease affecting hair follicles, was studied in C3H/HeJ mice and DEBR rats, which closely resemble the human condition. The disease involved histological changes in anagen follicles surrounded by mononuclear cells, primarily cytotoxic (CD8+) and helper (CD4+) T cells. Intralesional injection of triamcinolone acetonide significantly reduced this infiltration, leading to hair regrowth. The findings supported the hypothesis that alopecia areata is an autoimmune disease targeting hair follicles.
4 citations,
August 2019 in “Journal of Dermatology” The conclusion is that balancing cost and carbon emissions in hybrid power systems is crucial, especially when high reliability is needed, but the model needs to consider all device efficiencies and distribution losses.
2 citations,
December 2018 in “Journal of cosmetic dermatology” Higher CRBP1 levels are linked to more severe alopecia areata.
4 citations,
January 2014 in “Bone marrow transplantation” Alopecia areata can be transferred through stem cell transplants from affected siblings.
52 citations,
March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
5 citations,
June 1994 in “Journal of Cutaneous Pathology” No CD44 in alopecia areata, present in normal and androgenetic alopecia.
32 citations,
August 1984 in “Lancet”