Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata

August 2019 in “ Journal of Dermatology ”

Yura Lee, Bark-Lynn Lew, Woo-Young Sim, Jeongae Lee, Jongki Hong, Bong Hyun Chung

TLDR The conclusion is that balancing cost and carbon emissions in hybrid power systems is crucial, especially when high reliability is needed, but the model needs to consider all device efficiencies and distribution losses.

The 2019 document discussed a mathematical model for the optimal design and sizing of hybrid power systems (HPSs), considering uncertainties in renewable power sources and load demands. The model used chance-constrained programming and fuzzy optimization to balance economic and environmental goals and account for uncertainties. The study found a trade-off between cost and carbon emissions, with an increase in system reliability leading to higher costs and lower emissions. The model was able to solve all system reliability levels in 0.2 CPU seconds. The study concluded that demand uncertainty should not be overlooked, especially when high system reliability is required. However, the model did not account for the efficiencies of all power electronic devices or distribution losses, suggesting areas for future research.

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research Telogen Effluvium: Causes, Diagnosis, and Treatments

18 citations , March 2016 in “Cosmetics”

Telogen Effluvium is a condition causing excessive hair loss due to stress, illness, drugs, or hormonal changes, and can be treated with specific products or naturally resolves after 3-4 years.

research N1-Methylspermidine, A Stable Spermidine Analog, Prolongs Anagen And Regulates Epithelial Stem Cell Functions In Human Hair Follicles

13 citations , July 2015 in “Archives of dermatological research”

N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.

research Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis Through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model

22 citations , January 2014 in “Biological & Pharmaceutical Bulletin”

Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.

research Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis

5 citations , October 2013 in “Experimental Dermatology”

The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.

research Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness Between Korean and Caucasian Populations

10 citations , March 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions

61 citations , July 2011 in “PLOS ONE”

Spermidine may help reduce hair loss and deserves further testing as a treatment.

research Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp

30 citations , April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry”

Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.

research Polyamines and Hair: A Couple in Search of Perfection

30 citations , August 2010 in “Experimental Dermatology”

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

research Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration

25 citations , April 2006 in “British Journal of Dermatology”

Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.

research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle

185 citations , January 2006 in “Autoimmunity Reviews”

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

research Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness

47 citations , January 2001 in “Journal of Investigative Dermatology”

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

7 / 7 results

research Topical Tofacitinib for the Treatment of Alopecia Areata Affecting Facial Hair

7 citations , June 2021 in “British Journal of Dermatology”

Topical tofacitinib may effectively and safely regrow facial hair in some people with alopecia areata.

research Androgenetic Alopecia Pattern Hair Regrowth in Patients with Alopecia Areata Treated with Oral JAK Inhibitors

December 2020 in “Journal of The American Academy of Dermatology”

Oral JAK inhibitors help regrow hair in alopecia patients.

research Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata

4 citations , August 2019 in “Journal of Dermatology”

The conclusion is that balancing cost and carbon emissions in hybrid power systems is crucial, especially when high reliability is needed, but the model needs to consider all device efficiencies and distribution losses.

research Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers

70 citations , July 2016 in “Experimental Dermatology”

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

research Hair Diseases: Alopecia Areata and Androgenetic Alopecia

January 2010

Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.

research Alopecia Areata: Evidence-Based Treatments

71 citations , March 2009 in “Seminars in cutaneous medicine and surgery”

Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.

research Treatments for Androgenetic Alopecia and Alopecia Areata

72 citations , January 2001 in “Drugs”

Minoxidil and finasteride treat hair loss; more research needed for other options.