Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata

    August 2019 in “ Journal of Dermatology ”
    Yura Lee, Bark-Lynn Lew, Woo-Young Sim … Bong Hyun Chung
    Studysummary This study found that polyamine levels in hair samples differ between androgenic alopecia and alopecia areata, suggesting potential non-invasive biomarkers to distinguish between these hair loss conditions.
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    Research cited in this study 16

    1. Telogen Effluvium: Causes, Diagnosis, and Treatments Cosmetics · 2016
    2. N1-Methylspermidine, A Stable Spermidine Analog, Prolongs Anagen And Regulates Epithelial Stem Cell Functions In Human Hair Follicles Archives of dermatological research · 2015
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    4. Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis Experimental Dermatology · 2013
    5. Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis Experimental Dermatology · 2013
    6. Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness Between Korean and Caucasian Populations ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    7. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011
    8. Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry · 2011
    9. Polyamines and Hair: A Couple in Search of Perfection Experimental Dermatology · 2010
    10. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    11. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005
    12. Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness Journal of Investigative Dermatology · 2001
    13. Determination of Estrone and 17β-Estradiol in Human Hair by Gas Chromatography–Mass Spectrometry The Analyst · 2000
    14. GC-MS Determination of Steroids Related to Androgen Biosynthesis in Human Hair with Pentafluorophenyldimethylsilyl–Trimethylsilyl Derivatisation The Analyst · 1999
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    16. Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition Journal of Investigative Dermatology · 1996

    Related research 8

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    3. Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata Journal of Dermatology · 2019
    4. Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers Experimental Dermatology · 2016
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