Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis

    October 2013 in “ Experimental Dermatology ”
    Yuval Ramot, Leah A. Vardy
    Studysummary This study observed that putrescine and HR form a negative feedback mechanism affecting hair cycling, indicating a significant connection between HR, polyamines, and hair growth regulation.
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    Research cited in this study 12

    1. Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis Experimental Dermatology · 2013
    2. Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm Journal of Investigative Dermatology · 2011
    3. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011
    4. Marie Unna Hereditary Hypotrichosis Caused by a Novel Mutation in the Human Hairless Transcript Experimental Dermatology · 2010
    5. Polyamines and Hair: A Couple in Search of Perfection Experimental Dermatology · 2010
    6. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    7. Hairless Is a Nuclear Receptor Corepressor Essential for Skin Function Nuclear Receptor Signaling · 2009
    8. Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling Proceedings of the National Academy of Sciences of the United States of America · 2005
    9. Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase Journal of Investigative Dermatology · 2001
    10. Ornithine Decarboxylase Transgenic Mice as a Model for Human Atrichia with Papular Lesions Experimental dermatology · 2000
    11. Dynamic Expression of Ornithine Decarboxylase in Hair Growth Mechanisms of Development · 1999
    12. Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity Journal of Investigative Dermatology · 1996

    Related research 5

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    2. Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis Experimental Dermatology · 2013
    3. Fullerene Nanomaterials Potentiate Hair Growth Nanomedicine · 2009
    4. Expression of MK6a Dominant-Negative and C-Terminal Mutant Transgenes in Mice Has Distinct Phenotypic Consequences in the Epidermis and Hair Follicle Differentiation · 1999
    5. Topical Spermine And Putrescine Stimulated DNA Synthesis In The Hairless Mouse Epidermis British Journal of Dermatology · 1980