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GlossaryPutrescine

foul-smelling compound from amino acid breakdown in organisms

Putrescine is a foul-smelling organic compound that is produced during the breakdown of amino acids in living and dead organisms. It is one of the polyamines involved in cellular metabolism and is often associated with the process of tissue decomposition. In a biological context, putrescine plays a role in cell growth and differentiation, but its accumulation can be indicative of pathological conditions or tissue damage.

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research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis

10 citations , August 2013 in “Experimental Dermatology”

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis

research Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis

5 citations , October 2013 in “Experimental Dermatology”

The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.

research Expression and Distribution Patterns of Spermine, Spermidine, and Putrescine in Rat Hair Follicle

2 citations , November 2017 in “Histochemistry and Cell Biology”

Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.

research Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase

124 citations , July 1997 in “Journal of Biological Chemistry”

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

research Targeted Expression of Spermidine/Spermine N1-Acetyltransferase Increases Susceptibility to Chemically Induced Skin Carcinogenesis

54 citations , February 2002 in “Carcinogenesis”

Increasing SSAT makes skin more prone to cancer.

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