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GlossaryPutrescine

foul-smelling compound from amino acid breakdown in organisms

Putrescine is a foul-smelling organic compound that is produced during the breakdown of amino acids in living and dead organisms. It is one of the polyamines involved in cellular metabolism and is often associated with the process of tissue decomposition. In a biological context, putrescine plays a role in cell growth and differentiation, but its accumulation can be indicative of pathological conditions or tissue damage.

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research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis

10 citations, August 2013 in “Experimental Dermatology”

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

research Topical Spermine And Putrescine Stimulated DNA Synthesis In The Hairless Mouse Epidermis

10 citations, July 1980 in “British Journal of Dermatology”

Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.

research Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis

5 citations, October 2013 in “Experimental Dermatology”

The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.

research Expression and Distribution Patterns of Spermine, Spermidine, and Putrescine in Rat Hair Follicle

2 citations, November 2017 in “Histochemistry and Cell Biology”

Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.

research Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase

54 citations, May 2001 in “Journal of Investigative Dermatology”

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

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