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    Glossary Putrescine

    foul-smelling compound from amino acid breakdown in organisms

    Putrescine is a foul-smelling organic compound that is produced during the breakdown of amino acids in living and dead organisms. It is one of the polyamines involved in cellular metabolism and is often associated with the process of tissue decomposition. In a biological context, putrescine plays a role in cell growth and differentiation, but its accumulation can be indicative of pathological conditions or tissue damage.

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    Research 30 of 88

    1. Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis Experimental Dermatology · 2013 · 10 citations
    2. Topical spermine and putrescine stimulated DNA synthesis in the hairless mouse epidermis British Journal of Dermatology · 1980 · 10 citations
    3. Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis Experimental Dermatology · 2013 · 5 citations
    4. Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle Histochemistry and Cell Biology · 2017 · 2 citations
    5. Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase Journal of Biological Chemistry · 1997 · 124 citations
    6. Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis Carcinogenesis · 2002 · 54 citations
    7. Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase Journal of Investigative Dermatology · 2001 · 54 citations
    8. Vertebral epidermal transamidases Biochimica et Biophysica Acta (BBA) - Protein Structure · 1974 · 49 citations
    9. Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis Carcinogenesis · 2006 · 37 citations
    10. Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures as a Result of Spermidine/Spermine N1-Acetyltransferase Overexpression Journal of Investigative Dermatology · 2005 · 37 citations
    11. Polyamines and hair: a couple in search of perfection Experimental Dermatology · 2010 · 30 citations
    12. Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. PubMed · 2003 · 26 citations
    13. Biochemical features of primary cells from a pediatric patient with a gain-of-function <i>ODC1</i> genetic mutation Biochemical Journal · 2019 · 15 citations
    14. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 13 citations
    15. Synthetic studies toward the development of novel minoxidil analogs and conjugates with polyamines Tetrahedron Letters · 2010 · 12 citations
    16. Increased hair polyamine levels in patients with alzheimer's disease Annals of neurology · 2001 · 10 citations
    17. Bachmann–Bupp syndrome and treatment 2023
    18. The RATIOnal Role of Polyamines in Epidermal Differentiation Journal of Investigative Dermatology · 2021
    19. Regulation of Hematopoietic Cell Development and Hair Growth in Mouse Models: Expression Analysis of Tudor-SN and Polyamine-Regulated Proteins Tampere University Institutional Repository (Tampere University) · 2013
    20. In this Issue Journal of Investigative Dermatology · 2001
    21. 14. 膠原病患者における心理状態の統計学的観察(第45回 日本心身医学会東北地方会 演題抄録) 心身医学 · 1999
    22. Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice Amino Acids · 2009 · 12 citations
    23. A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study Dermatology practical & conceptual · 2017 · 8 citations
    24. 033 IL-15 is an unexpected guardian of hair follicle immune privilege and promotes human hair growth ex vivo Journal of Investigative Dermatology · 2021
    25. Dermatological drugs, topical agents, and cosmetics Side effects of drugs annual · 1993
    26. Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA<sub>A</sub>Receptor Function and Seizure Susceptibility Journal of Neuroscience · 2002 · 269 citations
    27. Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi PLoS neglected tropical diseases · 2017 · 41 citations
    28. Novel cosmeceuticals from plants—An industry guided review Journal of Applied Research on Medicinal and Aromatic Plants · 2017 · 39 citations
    29. A method to improve the efficacy of topical eflornithine hydrochloride cream Drug Delivery · 2014 · 24 citations
    30. Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias Experimental Dermatology · 2018 · 22 citations