In this Issue
May 2001
in “
Journal of Investigative Dermatology
”
The document discussed several studies related to skin and hair conditions. One study used genetically modified mouse fibroblasts to explore keratinocyte growth and differentiation, identifying granulocyte macrophage-colony stimulating factor and keratinocyte growth factor as key mediators. Another study investigated hairlessness in transgenic mice, linking it to overaccumulation of putrescine due to altered polyamine metabolism, which affected the hair cycle. Additionally, a study on photoaging demonstrated that all-trans retinoic acid could repair photoaged skin by increasing fibrillin-1 production, suggesting its potential as a marker for evaluating skin repair treatments. These findings provided insights into molecular mechanisms and potential therapeutic strategies for skin and hair disorders.