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    Glossary Keratinocyte Growth Factor

    stimulates skin and hair cell growth and repair

    Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a protein that plays a crucial role in the growth and repair of skin and hair. It specifically stimulates the proliferation and differentiation of keratinocytes, which are the primary cells found in the outer layer of the skin and hair follicles. This makes KGF important in wound healing and potentially beneficial in treating conditions like alopecia.

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    Research 10 of 1000+

    1. Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. The EMBO Journal · 1993 · 265 citations
    2. Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia. PubMed · 1995 · 219 citations
    3. Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair 2000 · 113 citations
    4. Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera. 1995 · 66 citations
    5. Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid Molecular Therapy · 2014 · 23 citations
    6. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    7. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations
    8. Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes Nucleic Acid Therapeutics · 2018 · 11 citations
    9. Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model Frontiers in Medicine · 2025 · 8 citations
    10. Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli Microbial Cell Factories · 2023 · 5 citations
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