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    GlossaryKeratinocyte Hyperproliferation

    rapid and excessive growth of skin cells

    Keratinocyte hyperproliferation refers to the rapid and excessive growth of keratinocytes, which are the primary cells found in the outer layer of the skin. This condition is often associated with skin disorders like psoriasis, where the skin cells multiply too quickly, leading to thick, scaly patches.

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      learn Procyanidin

      bioflavonoid found in plants with antioxidant and hair stimulating properties

      learn Redensyl

      commercial product with a blend of mostly natural ingredients for hair regrowth

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Sandalore: a scientific homemade approch

       20 upvotes 6 years ago
      The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

      community Painkillers May Block Minoxidil

      in Research/Science  14 upvotes 1 week ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.