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Glossary Hair Growth Factors

naturally occurring proteins that stimulate hair follicle growth

Hair Growth Factors are naturally occurring proteins or compounds that stimulate hair follicles to enter the growth phase, promoting hair development and reducing hair loss. These factors, such as keratinocyte growth factor (KGF) and vascular endothelial growth factor (VEGF), play crucial roles in cellular signaling pathways that regulate the hair growth cycle, making them essential in both clinical treatments for alopecia and cosmetic hair care products.

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Research

5 / 1000+ results

research Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia.

219 citations , July 1995 in “PubMed”

This study found that recombinant keratinocyte growth factor (rKGF) stimulated hair growth and provided a protective effect against alopecia in murine models, suggesting its role in hair follicle development and regeneration.

research Local Injection of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) Alters Cyclic Growth of Murine Hair Follicles

109 citations , April 1998 in “Journal of Investigative Dermatology”

This study found that recombinant human HGF/SF injections altered hair follicle growth cycles and mildly promoted hair elongation in mice, depending on their hair cycle stage.

research Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.

107 citations , June 1997 in “PubMed”

In this study, disrupting the epidermal growth factor receptor in mice led to abnormal hair and skin development, characterized by disorganized hair follicles and systemic disease, providing a model for understanding EGFR's role in skin biology.

Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy

research Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy

100 citations , November 1996 in “Molecular Medicine Today”

This review discusses the role of growth factors and cytokines in hair follicle development and cycling, but reports no new clinical findings on treatments for hair growth disorders.

research Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle

94 citations , July 2003 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that continuous expression of epidermal growth factor in transgenic mice prevented hair follicles from entering the catagen phase, implicating EGF as a crucial regulator in hair cycle progression.

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Learn

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learn Vascular Endothelial Growth Factor

What is Vascular Endothelial Growth Factor (VEGF), and how does it support hair growth in alopecia? VEGF promotes hair growth by enhancing blood supply to hair follicles.
Can products that stimulate Vascular Endothelial Growth Factor (VEGF) improve blood flow to hair follicles? Yes, products that stimulate VEGF may improve blood flow to hair follicles.

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor promotes hair growth by signaling cell survival and division.

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

learn Hair Transplant

How long does it take for transplanted hair to grow after a hair transplant? New hair growth after a transplant typically starts around 3-4 months.

learn Epidermal Growth Factor

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

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Community Join

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community How much hair growth potential can be lost due to lifestyle factors?

in Treatment 9 upvotes 11 months ago

Lifestyle factors like diet, stress, and nutrient deficiencies can impact hair regrowth, but their effects vary among individuals. Treatments mentioned include finasteride, dutasteride, and minoxidil.

community Does applying Epidermal Growth Factor (EGF) make a difference in hair growth?

4 upvotes 3 years ago

Applying Epidermal Growth Factor (EGF) topically may improve skin and potentially promote scalp health and hair growth, especially after microneedling. The user shares their positive experience with EGF and provides a product link.

community Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth

1 year ago

Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.

community GFM Gel - High concentration topical gel of Mimicking Growth Factors (GFm), a complex of polypeptides that mimic the action of endogenous growth factors and promote physiological hair regrowth. Helps strengthen the hair bulb and redensify the hair.

6 upvotes 1 year ago

The conversation discusses using GFM Gel, a topical gel with polypeptides that mimic growth factors to promote hair regrowth and strengthen hair. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community Cold and Japanese researchers. The Japanese began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor).

36 upvotes 1 year ago

Cold shock therapy may promote hair growth, but cold alone is not effective. Combining treatments like minoxidil, finasteride, cold showers, spicy foods, and exercise may enhance results.

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