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Glossary Hair Growth-Related Genes

specific genes that regulate hair follicle development and cycling

Hair Growth-Related Genes are specific genes that play a crucial role in regulating the development, cycling, and maintenance of hair follicles. These genes influence various biological processes such as cell proliferation, differentiation, and signaling pathways that are essential for hair growth. Mutations or variations in these genes can lead to conditions like alopecia or other hair growth disorders.

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Research

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research Investigation of the differential effect of juice or water extract from Puerariae Radix on hair growth related-genes in dermal papilla cells

January 2018 in “The Korea Journal of Herbology”

This study found that water extract of Puerariae Radix may promote hair growth by increasing the mRNA expression levels of hair growth-related genes in human dermal papilla cells, unlike the juice extract.

research Change in Hair Growth-related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-alpha Reductase Inhibitors, Dutasteride and Finasteride, in the Presence of Testosterone

January 2019

This study suggests that 5AR inhibitors may reverse decreased expression of growth factor genes in human hair follicles under testosterone stimulation, indicating involvement of type I 5AR in hair growth.

research Effect of Melatonin on Genes Including FGF5 That Related to Hair Growth in Cashmere Goat Skin

June 2012

This study observed that melatonin significantly increases FGF5 expression in cashmere goat skin, which may influence hair growth-related gene interactions differently than in other animals.

The Expression of Phosphorus-Responsive Genes Is Related to Root Hair Growth

research The Expression of P-Responsive Genes is Related to Root Hair Growth

1 citations , April 2009 in “The Proceedings of the International Plant Nutrition Colloquium XVI”

This study found that phosphorus and nitrogen deprivation increased root hair length in Brassica carinata and induced the expression of certain P-responsive genes, such as LRR and PRP.

research Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone

1 citations , June 2021 in “Singapore Medical Journal”

This study suggests that type I 5-alpha reductase may also play a role in hair growth, with dutasteride potentially being more potent than finasteride in modulating key hair growth gene expressions.

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Community Join

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community Bloodflow? Does it affect hair growth?

23 upvotes 7 years ago

Hair loss is primarily caused by genetic sensitivity to DHT, not lifestyle factors like diet or exercise. Treatments like Minoxidil and Finasteride can help, but it's important to consult a dermatologist to determine the best approach for individual cases.

community Intermittent fasting reduces hair growth?!? :(

35 upvotes 1 year ago

Intermittent fasting may inhibit hair growth by triggering a stress response that affects hair-follicle stem cells. Some users believe genetics and DHT play a larger role in hair loss, and treatments like Minoxidil and Finasteride are mentioned as ineffective for some.

community How long does it take after an environmental / lifestyle change for hair loss to actually slow down?

5 upvotes 10 months ago

Lifestyle changes may not significantly impact hair loss, as factors like DHT and genetics play a larger role. Some users suggest treatments like finasteride, dutasteride, and microneedling for hair growth.

community Why is Minoxidil not enough for hair loss? (No fin)

59 upvotes 1 year ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community The new growth in hair loss research: With increasing evidence of its impact on mental health, scientists are pushing forward with breakthroughs on balding. Later this year, scientists will launch one of the first ever clinical trials with hair follicles grown entirely from stem cells.

324 upvotes 7 years ago

Hair loss impacts mental health, with treatments like Minoxidil, finasteride, and stem cell transplants discussed. There is hope for future breakthroughs, but current treatments are limited, and awareness is lacking.

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Learn

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learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn Epidermal Growth Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn sh-Polypeptide-7

learn Fluridil

a topical anti-androgen with less systemic involvement

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

learn Pyrithione Zinc

How does pyrithione zinc help reduce dandruff and irritation related to hair loss? Pyrithione zinc reduces dandruff and irritation by inhibiting yeast growth on the scalp.

learn Hair Transplant

What are the risks and side effects of FUE hair transplants? Providers describe most FUE side effects, such as swelling, redness, numbness and shock loss, as temporary, but FUE is surgery and the same sources report pain, infection, folliculitis and small permanent donor-site scars. Longer-lasting problems, including visible donor-area thinning or poor graft growth, are possible and are not covered by this provider survey.
When will I see new hair growth after a hair transplant? New hair growth usually starts 2-4 months after a hair transplant.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

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Clinics

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Experts

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Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas